DEPARTMENT OF THE NAVY
OFFICE OF THE CHIEF OF NAVAL OPERATIONS
2000 NAVY PENTAGON
WASHINGTON, DC 20350-2000
OPNAVINST 5530.16B
N4
19 Jul 2021
OPNAV INSTRUCTION 5530.16B
From: Chief of Naval Operations
Subj: MINIMUM SECURITY STANDARDS FOR SAFEGUARDING BIOLOGICAL
SELECT AGENTS AND TOXINS
Ref: (a) DoDI 5210.88 of 26 May 2020
(b) SECNAVINST 5510.30C
Encl: (1) Biological Select Agents and Toxins and Biological Personnel Reliability Program
Forms
(2) Navy Biological Personnel Reliability Program Annual Status Report
1. Purpose. To prescribe Department of Defense (DoD) policy, procedures and responsibilities
for the Navy Biological Select Agents and Toxins (BSAT) Security Program per references (a)
and (b). This Instruction implements DoD physical security requirements pertaining to the use,
possession, storage, handling, transport, transfer, receipt or destruction of BSAT. This
instruction is a complete revision and should be reviewed in its entirety.
2. Cancellation. OPNAVINST 5530.16A.
3. Background.
a. This instruction was developed in conjunction with reference (a). It includes guidance
issued by DoD which was derived from the Code of Federal Regulations (CFR), United States
Department of Agriculture, Department of Commerce and Department of Health and Human
Services.
b. The objectives of this instruction are to:
(1) Establish policy for the minimum security of BSAT at Navy facilities by
implementing all requirements prescribed in reference (a).
(2) Provide guidance and standards for Navy military, civilian and contractors with
access to BSAT.
(3) Provide guidance and standards for the protection of Navy facilities housing BSAT
material and for the transportation of BSAT material under Navy cognizance.
